Endocrine Abstracts

It is not possible even with the most intensive conventional insulin regimens to control Type 1 diabetes well enough to normalise metabolic control or totally prevent complications. For this, a closed loop is needed, whereby circulating insulin levels are regulated on a moment to moment basis according to needs. Only pancreatic transplantation currently achieves this. Over 20000 whole pancreas transplants have been done worldwide and a one year graft survival rate of over 80% ...